OPTN antibody (AA 504-554)

Catalog No. ABIN7451913

This anti-OPTN antibody is a Rabbit Polyclonal antibody detecting OPTN in WB and IP. Suitable for Human.

Quick Overview for OPTN antibody (AA 504-554) (ABIN7451913)

Target: OPTN (Optineurin (OPTN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPTN antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-OPTN Antibody

Binding Specificity: AA 504-554

Purpose: Rabbit anti-Optineurin Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 504 and 554

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for OPTN

Target: OPTN (Optineurin (OPTN))

Alternative Name: Optineurin

Background: Background: Defects in optineurin have been linked to glaucoma. In the cell, optineurin localizes to the Golgi and associates with markers of the endocytic pathway. A role in membrane trafficking and golgi function has been proposed due to its association with the actin-based motor protein myosin VI and its function as an effector protein of the small GTPase Rab8.

Gene ID: 10133

NCBI Accession: NP_068815

UniProt: Q96CV9

Pathways: M Phase